Synthesis of optimal control in a mathematical model of tumour–immune dynamics

DOI10.1002/oca.2103zbMath1319.49063OpenAlexW1796057109MaRDI QIDQ5254096

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Publication date: 8 June 2015

Published in: Optimal Control Applications and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/oca.2103

zbMATH Keywords

optimal controlPontryagin's maximum principleswitching surfacechemotherapeutic agentlinear pharmacokinetic equationtumour-immune dynamics

Mathematics Subject Classification ID

Applications of optimal control and differential games (49N90) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Control problems involving ordinary differential equations (34H05) Optimality conditions for problems involving ordinary differential equations (49K15)

Related Items (5)

Optimal bounded noisy feedback control for damping random vibrations ⋮ Control of input‐affine nonlinear systems via linear programming ⋮ On a multiobjective optimal control of a tumor growth model with immune response and drug therapies ⋮ Maximization of viability time in a mathematical model of cancer therapy ⋮ Generalization of Cauchy's characteristics method to construct smooth solutions to Hamilton-Jacobi-Bellman equations in optimal control problems with singular regimes

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