LDAcoop (Q5981218)
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Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | LDAcoop |
Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation |
Statements
Cellular cooperation compromises the established method ofcalculating clonogenic activity from limiting dilution assay (LDA) data.This tool provides functions that enable robust analysis in presence orabsence of cellular cooperation. The implemented method incorporates thesame cooperativity module to model the non-linearity associated withcellular cooperation as known from the colony formation assay (Brix et al.(2021) <doi:10.1038/s41596-021-00615-0>: "Analysis of clonogenic growth invitro." Nature protocols).
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9 October 2023
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