Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation (Q527819)
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| Language | Label | Description | Also known as |
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| English | Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation |
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Boundary integral formulation and semi-implicit scheme coupling for modeling cells under electrical stimulation (English)
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12 May 2017
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The authors are concerned with numerical solutions to an unsteady transmission problem for the Laplace operator with a dynamic boundary condition on a smooth interface (the temporal behavior of potential jumps across the membrane). They cast the original volume model, using the boundary multiple traces formulation for time dependent variables, into a system of integral equations. Then they solve it by a Galerkin method along with a semi-implicit second-order time-stepping and analyze the stability and convergence. Some numerical experiments for two-dimensional cells are carried out.
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biological cell
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electrical stimulation
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Laplace equation
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unsteady transmission problem
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Hodgkin-Huxley model
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boundary integral formulation
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existence
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uniqueness
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Galerkin method
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second-order time-stepping
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stability
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convergence
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numerical experiments
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