Global solutions of some chemotaxis and angiogenesis system in high space dimension (Q862014)

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Global solutions of some chemotaxis and angiogenesis system in high space dimension
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    Global solutions of some chemotaxis and angiogenesis system in high space dimension (English)
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    2 February 2007
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    The authors investigate the existence of the global (in time) weak solutions of two chemotaxis models, where the spatial variable belongs to \(\mathbb R^d\), (\(d\geq 2\)). The first model is the parabolic-elliptic system (called \`\` chemotaxis system\'\'): \[ \begin{aligned}\frac{\partial n}{\partial t}=&\kappa\Delta n-\chi\nabla\cdot[n\nabla c],\,\,\,t>0,\\ -\Delta c=&n-\alpha c,\,\,\,t>0,\\ n(0,x)=&n_0(x),\end{aligned} \] where \(\alpha\geq 0\), the diffusion coefficient \(\kappa\) is constant and the chemotactic sensitivity function \(\chi\) is constant with respect to the chemical density. The second model is the parabolic-degenerate system (called ``angiogenesis system''): \[ \begin{aligned}\frac{\partial n}{\partial t}=&\kappa\Delta n-\nabla\cdot [n\chi(c)\nabla c],\,\,\,t>0,\\\frac{\partial c}{\partial t}=&-c^mn,\,\,\,t>0,\\n(0,x)=&n_0(x),\,\,\,c(0,x)=c_0(x),\end{aligned} \] where \(m\) is a positive parameter (\(m\geq 1\)), the diffusion coeficient \(\kappa\) is still constant and \(\chi\) is a given positive function on \(\mathbb R^+\) of the form \(\chi(c)=\delta c^{-\alpha}\), \(\delta>0\), \(0<\alpha<1\), or \(\chi(c)=\frac{\beta}{\alpha+\beta c}\), with \(\alpha,\,\beta>0\). The above systems are subject to some decay conditions at infinity of the densities \(n\) and \(c\). For both problems it is proved that when the initial data are small enough (in the \(L^{d/2}\) norm), then the weak solutions \(n\) are bounded in \(L^{\infty}(\mathbb R^+;L^p(\mathbb R^d))\), with \(p\geq \text{max}\{1,d/2-1\}\). If \(d\geq 3\), a blow-up result is also presented for the first problem, and for \(d=2\) the existence of the weak solutions to the second problem is obtained even for large initial data.
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    chemotaxis
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    angiogenesis
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    degenerate parabolic equations
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    global weak solutions
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    blow-up
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