An analysis of functional curability on HIV infection models with Michaelis-Menten-type immune response and its generalization (Q521485)
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English | An analysis of functional curability on HIV infection models with Michaelis-Menten-type immune response and its generalization |
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An analysis of functional curability on HIV infection models with Michaelis-Menten-type immune response and its generalization (English)
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11 April 2017
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In this verbose paper, the author considers an ODE model for HIV with 4 variables: density of susceptible target cells, density of infected target cells, density of viruses, and density of immune effector cells. The dependence of the number of fixed points and their stability on parameters is determined, concentrating on the case where two stable fixed points coexist. (Functional curability refers to this situation, where the hope is that the system can be moved from a high-viral-load state to a low-viral-load state.)
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virus dynamics
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HIV infection
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AIDS
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functional cure
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hepatitis B virus infection
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