A dichotomy for a class of cyclic delay systems

DOI10.1016/J.MBS.2006.09.022MaRDI QIDQ2643252zbMATH OpenOpenAlexWikidataFDO

Authors Germán A. Enciso

Publication date 23 August 2007

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/q-bio/0601015

zbMATH Keywords

delay systemsHill functionsHopf bifurcationnegative feedbackSchwarzian derivative

Mathematics Subject Classification ID

Monotone systems involving ordinary differential equations (34C12) Bifurcation theory for ordinary differential equations (34C23) Control problems for functional-differential equations (34K35) Nonlinear systems in control theory (93C10)

Abstract: Two complementary analyses of a cyclic negative feedback system with delay are considered in this paper. The first analysis applies the work by Sontag, Angeli, Enciso and others regarding monotone control systems under negative feedback, and it implies the global attractiveness towards an equilibrium for arbitrary delays. The second one concerns the existence of a Hopf bifurcation on the delay parameter, and it implies the existence of nonconstant periodic solutions for special delay values. A key idea is the use of the Schwarzian derivative, and its application for the study of Michaelis-Menten nonlinearities. The positive feedback case is also addressed.

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Cited in

(10)

• Transversality for cyclic negative feedback systems
• A cyclic system with delay and its characteristic equation
• Absence of small solutions and existence of Morse decomposition for a cyclic system of delay differential equations
• Periodic solutions for an N-dimensional cyclic feedback system with delay
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