A multiple comparison procedure for hypotheses with gatekeeping structure

DOI10.1093/BIOMET/ASS083MaRDI QIDQ5411035zbMATH OpenOpenAlexFDO

Authors Xiaolong Luo, Guang Chen, Soo Peter Ouyang, Bruce W. Turnbull

Publication date 22 April 2014

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/ass083

zbMATH Keywords

clinical trialsscorrelationsgatekeeping procedurenonparametrics

Mathematics Subject Classification ID

Nonparametric estimation (62G05) Measures of association (correlation, canonical correlation, etc.) (62H20) Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• General Multistage Gatekeeping Procedures
• General theory of mixture procedures for gatekeeping
• Gatekeeping testing via adaptive alpha allocation
• Development of gatekeeping strategies in confirmatory clinical trials
• Bonferroni parallel gatekeeping -- transparent generalizations, adjusted p-values, and short direct proofs

Cited in

(8)

• Development of gatekeeping strategies in confirmatory clinical trials
• The union closure method for testing a fixed sequence of families of hypotheses
• A simple and flexible Holm gatekeeping procedure
• General theory of mixture procedures for gatekeeping
• Graphical approaches for multiple comparison procedures
• Bonferroni parallel gatekeeping -- transparent generalizations, adjusted p-values, and short direct proofs
• Gatekeeping testing via adaptive alpha allocation
• Relations among three parametric multiple testing methods for correlated tests

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