A random effects model for binary mixture toxicity experiments

DOI10.1007/S13253-010-0041-7MaRDI QIDQ2260194zbMATH OpenOpenAlexWikidataFDO

Authors Helle Sørensen, Nina Cedergreen, Jens C. Streibig

Publication date 5 March 2015

Published in Journal of Agricultural, Biological and Environmental Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s13253-010-0041-7

zbMATH Keywords

meta-analysislikelihood ratio testinteractionsmall sample distributionsynergismantagonismconcentration additionconcentration-response curves

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

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Cites work

• A Unified Theory for Quantal Responses to Mixtures of Drugs: Non-Interactive Action
• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Empirical evaluation of sufficient similarity in dose-response for environmental risk assessment of chemical mixtures
• Nonlinear Response Surface and Mixture Experiment Methodologies Applied to the Study of Synergism
• Small sample distribution of the likelihood ratio test in the random effects model
• Testing for additivity in chemical mixtures using a fixed-ratio ray design and statistical equivalence testing methods

Cited in

(8)

• Analysis of a Toxicological Experiment Using a Generalized Linear Model with Nested Random Effects
• An additive stochastic model for two chemicals
• A Symmetric Extended Logistic Model with Applications to Experimental Toxicity Data
• Detecting departure from additivity along a~fixed-ratio mixture ray with a piecewise model for dose and interaction thresholds
• A novel method based on similarity and triangulation for predicting the toxicities of various binary mixtures
• Generalized concentration addition: a method for examining mixtures containing partial agonists
• scientific article; zbMATH DE number 1302816 (Why is no real title available?)
• A General Noninteractive Multiple Toxicity Model Including Probit, Logit, and Weibull Transformations

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• drc

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