A stochastic analysis of performance limits for optical microscopes

DOI10.1007/S11045-005-6237-2MaRDI QIDQ862453zbMATH OpenOpenAlexFDO

Authors Sripad Ram, E. Sally Ward, Raimund J. Ober

Publication date 24 January 2007

Published in Multidimensional Systems and Signal Processing (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial 4.0 International

Full work available at URL https://doi.org/10.1007/s11045-005-6237-2

zbMATH Keywords

parameter estimationFisher information matrixoptical imagingCramer-Rao lower boundsingle molecule microscopyfluorescence microscopylocalization accuracySpatio-temporal stochastic processes

Mathematics Subject Classification ID

Cell movement (chemotaxis, etc.) (92C17) Application models in control theory (93C95) Stochastic systems in control theory (general) (93E03) Identification in stochastic control theory (93E12) Physical optics (78A10)

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• Limits of accuracy for parameter estimation and localization in single-molecule microscopy via sequential Monte Carlo methods

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