adoptr

MaRDI QIDQ55966swMATHCRANFDO

Authors Kevin Kunzmann, Maximilian Pilz, Jan Meis, Nico Bruder

Last update 3 May 2026

Copyright license MIT license, File License

Software version identifier 0.1.1, 0.2.0, 0.2.2, 0.2.3, 0.3.0, 0.3.2, 0.4.1, 0.4.2, 1.0.0, PACKAGES.rds, 1.0.1, 1.1.0, 1.1.1, 1.1.2

Official website https://cran.r-project.org/web/packages/adoptr/index.html

Source code repository https://github.com/cran/adoptr

Description

Optimize one or two-arm, two-stage designs for clinical trials with respect to several implemented objective criteria or custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz et al. (2019) <doi:10.1002/sim.8291> and Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09> for details.

Cites work

• A variational approach to optimal two‐stage designs
• The adoptr Package: Adaptive Optimal Designs for Clinical Trials in R

Cited in

(6)

• SHELF
• OptGS
• AGSDest
• A note on the shape of sample size functions of optimal adaptive two-stage designs
• rpact
• adestr

This page was built for software: adoptr