An evolutionary theory of clonal senescence

DOI10.1006/TPBI.1995.1013MaRDI QIDQ1897487zbMATH OpenOpenAlexFDO

Authors Bård Pedersen

Publication date 29 August 1996

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1006/tpbi.1995.1013

zbMATH Keywords

natural selectionlife historyclonal level fitnessevolutionary theory of senescence of clonesramets

Mathematics Subject Classification ID

Problems related to evolution (92D15)

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(7)

• Agelessness is possible under the disposable soma theory but system complexity makes it unlikely
• Senescence as an adaptation to limit the spread of disease
• Novel features of computer-simulated clonal life of \textit{Paramecium caudatum}
• Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing
• The case for negative senescence
• Somatic mutations in organisms with complex life histories.
• Aging a little: on the optimality of limited senescence in \textit{Escherichia coli}

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