Analysis of comparative data with hierarchical autocorrelation

DOI10.1214/08-AOAS173MaRDI QIDQ958333zbMATH OpenOpenAlexWikidataFDO

Authors Cécile Ané

Publication date 3 December 2008

Published in The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/0804.3166

zbMATH Keywords

asymptotic convergenceBrownian motion evolutioncomparative methodconsistencydependencelinear modelphylogenetic tree

Mathematics Subject Classification ID

Asymptotic properties of parametric estimators (62F12) Estimation in multivariate analysis (62H12) Linear regression; mixed models (62J05) Analysis of variance and covariance (ANOVA) (62J10) Inference from stochastic processes (62M99) Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Abstract: The asymptotic behavior of estimates and information criteria in linear models are studied in the context of hierarchically correlated sampling units. The work is motivated by biological data collected on species where autocorrelation is based on the species' genealogical tree. Hierarchical autocorrelation is also found in many other kinds of data, such as from microarray experiments or human languages. Similar correlation also arises in ANOVA models with nested effects. I show that the best linear unbiased estimators are almost surely convergent but may not be consistent for some parameters such as the intercept and lineage effects, in the context of Brownian motion evolution on the genealogical tree. For the purpose of model selection I show that the usual BIC does not provide an appropriate approximation to the posterior probability of a model. To correct for this, an effective sample size is introduced for parameters that are inconsistently estimated. For biological studies, this work implies that tree-aware sampling design is desirable; adding more sampling units may not help ancestral reconstruction and only strong lineage effects may be detected with high power.

Recommendations

• Asymptotic theory with hierarchical autocorrelation: Ornstein-Uhlenbeck tree models
• Phylogenetic effective sample size
• Comparative methods based on species mean values.
• The impact of unsuspected serial correlations on model selection in linear regression
• scientific article; zbMATH DE number 426419

Cites work

• A new look at the statistical model identification
• A Reference Bayesian Test for Nested Hypotheses and its Relationship to the Schwarz Criterion
• Approximate Bayes factors and accounting for model uncertainty in generalised linear models
• Asymptotics for Analysis of Variance When the Number of Levels is Large
• Bayes Factors
• Bayesian model selection and model averaging
• Estimating the dimension of a model
• Gene regulatory networks: a discrete model of dynamics and topological evolution
• scientific article; zbMATH DE number 4215168 (Why is no real title available?)
• scientific article; zbMATH DE number 1158743 (Why is no real title available?)
• scientific article; zbMATH DE number 1865935 (Why is no real title available?)
• scientific article; zbMATH DE number 1405845 (Why is no real title available?)
• scientific article; zbMATH DE number 3393603 (Why is no real title available?)
• Linear Statistical Inference and its Applications
• Model Selection and Multimodel Inference
• Rank tests for anova with large number of factor levels
• The limiting distribution of theF-statistic from nonnormal universes
• The Selection of Prior Distributions by Formal Rules
• Towards reconciling two asymptotic frameworks in spatial statistics

Cited in

(15)

• Multi-task learning improves ancestral state reconstruction
• Ancestral state reconstruction with large numbers of sequences and edge-length estimation
• On the convergence of the maximum likelihood estimator for the transition rate under a 2-state symmetric model
• Interspecies correlation for neutrally evolving traits
• Phylogenetic confidence intervals for the optimal trait value
• Learning from non-iid data: fast rates for the one-vs-all multiclass plug-in classifiers
• A consistent estimator of the evolutionary rate
• Phylogenetic effective sample size
• Global multivariate model learning from hierarchically correlated data
• Asymptotic theory with hierarchical autocorrelation: Ornstein-Uhlenbeck tree models
• The phylogenetic effective sample size and jumps
• Adaptive trait evolution in random environment
• When can we reconstruct the ancestral state? Beyond Brownian motion
• When can we reconstruct the ancestral state? A unified theory
• A phylogenetic comparative method for studying multivariate adaptation

This page was built for publication: Analysis of comparative data with hierarchical autocorrelation

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q958333)