Approximation Methods for Inverse Problems Governed by Nonlinear Parabolic Systems
convergenceinverse problemsleast squares optimizationnonlinear parabolic systems with delaysnumerical resultsparameter estimationsemidiscrete Galerkin schemes
Nonlinear parabolic equations (35K55) Inverse problems for PDEs (35R30) Stability and convergence of numerical methods for initial value and initial-boundary value problems involving PDEs (65M12) Numerical methods for inverse problems for initial value and initial-boundary value problems involving PDEs (65M32) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Medical applications (general) (92C50)
The authors study the approximation of parameter estimation problems governed by nonlinear parabolic systems with delays, motivated by a concrete pharmacological application. The mathematical model is briefly presented: the detailed theoretical framework was considered by [\textit{H. T. Banks} and \textit{C. J. Musante} [Nonlinear Anal., Theory Methods Appl. 35A, No. -5, 629-648 (1999; Zbl 0928.35180)]. The main part of the work is devoted to give convergence of approximate optimal parameters and that of forward solutions in the context of semidiscrete Galerkin schemes. Some numerical results are presented, even in the case of noisy data.
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