Assessing treatment-selection markers using a potential outcomes framework

DOI10.1111/J.1541-0420.2011.01722.XMaRDI QIDQ4649041zbMATH OpenOpenAlexWikidataFDO

Authors Ying Huang, Peter B. Gilbert

Publication date 19 November 2012

Published in Biometrics (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc3417090

zbMATH Keywords

classification accuracypotential outcomesconstrained maximum likelihoodmonotone treatment effectsensitivity analysismarker

Mathematics Subject Classification ID

Point estimation (62F10) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Parametric inference under constraints (62F30)

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• The use of covariates and random effects in evaluating predictive biomarkers under a potential outcome framework
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Cites work

• A goodness-of-fit test for logistic regression models based on case-control data
• Adjusting for Nonignorable Drop-Out Using Semiparametric Nonresponse Models
• Combining several screening tests: optimality of the risk score
• Design and inference for cancer biomarker study with an outcome and auxiliary-dependent subsampling
• Does Finasteride Affect the Severity of Prostate Cancer? A Causal Sensitivity Analysis
• Evaluating Markers for Selecting a Patient's Treatment
• Goodness-of-fit tests for semiparametric biased sampling models
• Sensitivity Analysis for the Assessment of Causal Vaccine Effects on Viral Load in HIV Vaccine Trials

Cited in

(18)

• Evaluating Markers for Selecting a Patient's Treatment
• Identifying predictive markers for personalized treatment selection
• Tutorial in biostatistics: data-driven subgroup identification and analysis in clinical trials
• Evaluating marker-guided treatment selection strategies
• Combining biomarkers to optimize patient treatment recommendations
• Case-only approach to identifying markers predicting treatment effects on the relative risk scale
• Evaluation of biomarkers for treatment selection using individual participant data from multiple clinical trials
• The use of covariates and random effects in evaluating predictive biomarkers under a potential outcome framework
• Development and validation of biomarker classifiers for treatment selection
• Identification of subpopulations with distinct treatment benefit rate using the Bayesian tree
• A nonparametric method for value function guided subgroup identification via gradient tree boosting for censored survival data
• The area between ROC curves, a non-parametric method to evaluate a biomarker for patient treatment selection
• An approach to evaluating and comparing biomarkers for patient treatment selection
• Decomposing Treatment Effect Variation
• Designing a study to evaluate the benefit of a biomarker for selecting patient treatment
• Adaptive experiments toward learning treatment effect heterogeneity
• Comparing and combining biomarkers as principal surrogates for time-to-event clinical endpoints
• Analyzing longitudinal data to characterize the accuracy of markers used to select treatment

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