Bayesian correction for misclassification in multilevel count data models

DOI10.1155/2018/3212351MaRDI QIDQ1737303zbMATH OpenOpenAlexWikidataFDO

Authors Tyler Nelson, Joon Jin Song, Yoo-Mi Chin, James D. Stamey

Publication date 27 March 2019

Published in Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1155/2018/3212351

zbMATH Keywords

generalized linear modelmisclassificationmultilevel count data

Mathematics Subject Classification ID

Bayesian inference (62F15) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Paired and multiple comparisons; multiple testing (62J15) Diagnostics, and linear inference and regression (62J20) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Review text

Summary: Covariate misclassification is well known to yield biased estimates in single level regression models. The impact on hierarchical count models has been less studied. A fully Bayesian approach to modeling both the misclassified covariate and the hierarchical response is proposed. Models with a single diagnostic test and with multiple diagnostic tests are considered. Simulation studies show the ability of the proposed model to appropriately account for the misclassification by reducing bias and improving performance of interval estimators. A real data example further demonstrated the consequences of ignoring the misclassification. Ignoring misclassification yielded a model that indicated there was a significant, positive impact on the number of children of females who observed spousal abuse between their parents. When the misclassification was accounted for, the relationship switched to negative, but not significant. Ignoring misclassification in standard linear and generalized linear models is well known to lead to biased results. We provide an approach to extend misclassification modeling to the important area of hierarchical generalized linear models.

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Cites work

• A Bayesian approach for analyzing a cluster-randomized trial with adjustment for risk misclassification
• Bayesian sample size determination for binary regression with a misclassified covariate and no gold standard
• Modelling measurement errors and category misclassifications in multilevel models

Cited in

(5)

• A Bayesian approach for analyzing a cluster-randomized trial with adjustment for risk misclassification
• Bayesian hierarchical models for misaligned data: a simulation study
• On the estimation of the misclassification table for finite count data with an application in caries research
• Bayesian misclassification and propensity score methods for clustered observational studies
• A Bayesian adjustment for covariate misclassification with correlated binary outcome data

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