Buffering gene expression noise by microRNA based feedforward regulation

DOI10.1007/978-3-319-99429-1_8MaRDI QIDQ1796491zbMATH OpenOpenAlexFDO

Authors Pavol Bokes, Michal Hojcka, Abhyudai Singh

Publication date 17 October 2018

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1007/978-3-319-99429-1_8

zbMATH Keywords

gene expressionkinetic Monte Carlo simulationmicroRNA

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Recommendations

• Stabilizing gene regulatory networks through feedforward loops
• Propagation and control of gene expression noise with non-linear translation kinetics
• Gene expression noise is affected differentially by feedback in burst frequency and burst size
• Limits of noise for autoregulated gene expression
• A feedforward loop motif in transcriptional regulation: induction and repression

Cited in

(7)

• Independent channels for miRNA biosynthesis ensure efficient static and dynamic control in the regulation of the early stages of myogenesis
• Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network
• Modelling and analysis of a gene-regulatory feed-forward loop with basal expression of the second regulator
• Stochastic noise reduction upon complexification: positively correlated birth-death type systems
• Fluctuation effects in gene regulation by microRNAs and correlations between gene and pseudogene mRNAs in the control of cancer
• The role of gene regulation in redundant and synergistic information transfers in coherent feed-forward loop
• Maintenance of steady-state mRNA levels by a microRNA-based feed forward loop in the presence of stochastic gene expression noise

This page was built for publication: Buffering gene expression noise by microRNA based feedforward regulation

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1796491)