chestR
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ChestR
Description
Explores treatment effect heterogeneity and candidate predictive biomarkers by re-fitting weighted Cox proportional hazards models on a biomarker grid. Kernel weights centred at each grid point produce local coefficient estimates that can be visualised across biomarker space. Builds on ideas related to graphical Cox treatment-covariate interaction methods [see Bonetti and Gelber (2004) <doi:10.1093/biostatistics/kxh002> and local partial-likelihood approaches Fan, Lin and Zhou (2006) <doi:10.1214/009053605000000796>].
This page was built for software: chestR
