Exact analysis of a paired sibling data

DOI10.1007/BF02753910MaRDI QIDQ1775981zbMATH OpenOpenAlexFDO

Authors I. H. Dinwoodie, Brenda Macgibbon

Publication date 20 May 2005

Published in Computational Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf02753910

zbMATH Keywords

categorical dataexact conditional testexponential familyfittinggenetic dataMonte-Carlo methodsquasi-independencesibling pair datastructural zeros

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Monte Carlo methods (65C05) Numerical smoothing, curve fitting (65D10) Data structures (68P05)

Review text

The authors discuss the problem of statistical analysis of genetic study of sibling pair data of \textit{F. C. Fraser} and \textit{A. D. Hunter} [Etiologic relations among categories of congenital heart malformations. The American Journal of Cardiology 36, 793--796 (1975)]. The data is in the form of a triangular table with vanishing diagonal entries, so the problem of fitting parametric models to such tables is investigated using Monte-Carlo methods. Exact \(p\)-values are computed for a test of parameter significance and a test of goodness-of-fit which contradict the model of quasi-independence and confirm the previous analysis by \textit{B. MacGibbon} [A log-linear model of a paired sibling study. In Proceedings of Statistics'81 Canada Conference, Eds. Y. Chaubey, T. D. Dwivedi, 193-197 (1983)].

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Cites work

• A survey of exact inference for contingency tables. With comments and a rejoinder by the author
• Exact Conditional Tests of Quasi-Independence for Triangular Contingency Tables: Estimating Attained Significance Levels
• Generating functions for exact p-values of odds ratios in logistic regression
• On Obtaining Permutation Distributions in Polynomial Time
• Studies in the history of probability and statistics XLIII Karl Pearson and quasi-independence
• The Analysis of Cross-Classified Data: Independence, Quasi-Independence, and Interactions in Contingency Tables with or Without Missing Entries

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(2)

• Graph partitioning by correspondence analysis and taxicab correspondence analysis
• Analysis of Twin Data Using SAS

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