Genetic recombination as a generalised gradient flow

DOI10.1007/S00605-021-01612-XMaRDI QIDQ2665272zbMATH OpenOpenAlexFDO

Authors Frederic Alberti

Publication date 18 November 2021

Published in Monatshefte für Mathematik (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/2009.09688

zbMATH Keywords

chemical reaction networksgradient flowLyapunov functionpartitioning processrecombination

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

Abstract: It is well known that the classical recombination equation for two parent individuals is equivalent to the law of mass action of a strongly reversible chemical reaction network, and can thus be reformulated as a generalised gradient system. Here, this is generalised to the case of an arbitrary number of parents. Furthermore, the gradient structure of the backward-time partitioning process is investigated.

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Cites work

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Cited in

(8)

• The evolution of a population under recombination: how to linearise the dynamics
• The geometry of recombination
• Invariant measures of genetic recombination processes
• Moment closure in a Moran model with recombination
• Genetic recombination as a chemical reaction network
• The recombination equation for interval partitions
• A general reduction principle for genetic modifiers of recombination
• Nonlinear recombinations and generalized random transpositions

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