Genomic signals of reoriented ORFs

DOI10.1155/S1110865704309169MaRDI QIDQ1773705zbMATH OpenFDO

Authors Paul Dan Cristea

Publication date 3 May 2005

Published in EURASIP Journal on Applied Signal Processing (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1155/S1110865704309169

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Biomedical imaging and signal processing (92C55) Genetics and epigenetics (92D10)

Review text

Summary: Complex representation of nucleotides is used to convert DNA sequences into complex digital genomic signals. The analysis of the cumulated phase and unwrapped phase of DNA genomic signals reveals large-scale features of eukaryote and prokaryote chromosomes that result from statistical regularities of base and base-pair distributions along DNA strands. By reorienting the chromosome coding regions, a `hidden' linear variation of the cumulated phase has been revealed, along with the conspicuous almost linear variation of the unwrapped phase. A model of chromosome longitudinal structure is inferred on these bases.

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Cited in

(2)

• Large-scale chromosome folding versus genomic DNA sequences: a discrete double Fourier transform technique
• Large scale features in DNA genomic signals

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