Inference for one-step beneficial mutations using next generation sequencing

DOI10.1515/SAGMB-2014-0030MaRDI QIDQ2258450zbMATH OpenOpenAlexWikidataFDO

Authors Andrzej J. Wojtowicz, Craig R. Miller, Paul Joyce

Publication date 26 February 2015

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc5563372

zbMATH Keywords

next generation sequencingexperimental evolutionadaptive evolutionone-step benefical mutationsselection coefficients

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cites work

• scientific article; zbMATH DE number 3567782 (Why is no real title available?)
• A simple stochastic gene substitution model
• Fitting the Generalized Pareto Distribution to Data
• Model of effectively neutral mutations in which selective constraint is incorporated
• Statistical inference using extreme order statistics

Cited in

(5)

• Extracting viability landscapes from mutagen-response experiments
• Statistical questions in experimental evolution
• Estimation of the rate and effect of new beneficial mutations in asexual populations
• Quantifying selection in evolving populations using time-resolved genetic data
• Estimating the number of one-step beneficial mutations

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