VEwaningVariant (Q106196)

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Vaccine Efficacy Over Time - Variant Aware
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    VEwaningVariant
    Vaccine Efficacy Over Time - Variant Aware

      Statements

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      1.3
      7 June 2022
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      1.1
      4 November 2021
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      1.2
      17 January 2022
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      1.4
      13 December 2023
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      13 December 2023
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      Implements methods for inference on potential waning of vaccine efficacy and for estimation of vaccine efficacy at a user-specified time after vaccination based on data from a randomized, double-blind, placebo-controlled vaccine trial in which participants may be unblinded and placebo subjects may be crossed over to the study vaccine. The methods also for variant stratification and allow adjustment for possible confounding via inverse probability weighting through specification of models for the trial entry process, unblinding mechanisms, and the probability an unblinded placebo participant accepts study vaccine.
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      Marie Davidian
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      A.a. Tsiatis
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