Probabilistic models of genome shuffling (Q1111971)
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scientific article; zbMATH DE number 4077020
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| English | Probabilistic models of genome shuffling |
scientific article; zbMATH DE number 4077020 |
Statements
Probabilistic models of genome shuffling (English)
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1989
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The comparison of entire genomes in evolutionary studies gives rise to alignments characterized by many intersections, or inversions in the order of two fragments in different genomes. To model this, we suggest a random migration process for fragments, and discuss its equilibrium distribution in the case of linear and circular genomes. Simulations are carried out to explore ``cut-off'' behavior as the process approaches equilibrium. We define a new process to take into account the indistinguishability of two fragments which are adjacent in both genomes being compared. Questions of applicability of these models are discussed.
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fragment alignments
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sequence comparison
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comparison of entire genomes
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random migration process for fragments
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equilibrium distribution
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linear and circular genomes
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Simulations
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0.7487395405769348
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0.7463571429252625
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0.7463571429252625
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0.7294022440910339
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