Global dynamics of an HTLV-1 model with cell-to-cell infection and mitosis (Q1722149)
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scientific article; zbMATH DE number 7021779
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| English | Global dynamics of an HTLV-1 model with cell-to-cell infection and mitosis |
scientific article; zbMATH DE number 7021779 |
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Global dynamics of an HTLV-1 model with cell-to-cell infection and mitosis (English)
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14 February 2019
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Summary: A mathematical model of human T-cell lymphotropic virus type 1 in vivo with cell-to-cell infection and mitosis is formulated and studied. The basic reproductive number \(R_0\) is derived. It is proved that the dynamics of the model can be determined completely by the magnitude of \(R_0\). The infection-free equilibrium is globally asymptotically stable (unstable) if \(R_0 < 1\) (\(R_0 > 1\)). There exists a chronic infection equilibrium and it is globally asymptotically stable if \(R_0 > 1\).
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HTLV-1 model
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cell-to-cell infection
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mitosis
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global stability
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0.9134403467178344
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0.9021985530853271
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0.9021985530853271
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0.894906759262085
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