Relatedness and inclusive fitness with inbreeding (Q1803895)

This paper deals with the concept of relatedness introduced by W. D. Hamilton which is relevant to the theory of kin selection and altruism. In diploid populations without inbreeding, the coefficient of relatedness between a donor \(I\) and a recipient \(J\) is defined as the expected fraction of genes in the recipient identical by descent to one or more genes in the donor at a given locus, and can be expressed by Malecot's coefficient of kinship or equivalently by Wright's correlation coefficient of relationship. With inbreeding, however, relatedness is not a symmetric relation any more. The coefficient of relatedness of \(I\) to \(J\) is deduced as a covariance ratio and expressed in terms of identity coefficients and average allelic effects on altruism propensity in totally inbred and totally outbred populations. Moreover, a measure of relatedness is proposed by a variable based on two pedigree indices corresponding to measures of relatedness in Hamilton's original sense in cases of inbred and outbred donors. This measure depends only on the pedigree by which donors and recipients are connected, and allows for a description of kin selection models with inbreeding in terms of inclusive fitness.