A coupled 3D-1D multiscale Keller-Segel model of chemotaxis and its application to cancer invasion (Q2090475)
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| Language | Label | Description | Also known as |
|---|---|---|---|
| English | A coupled 3D-1D multiscale Keller-Segel model of chemotaxis and its application to cancer invasion |
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A coupled 3D-1D multiscale Keller-Segel model of chemotaxis and its application to cancer invasion (English)
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25 October 2022
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A Keller-Segel type system has been proposed to model the invasion of metastatic cancer cells in the extracellular matrix with a network of fibers. Mathematically, this leads to a coupled system of 3D and 1D chemotaxis type equations. The multiscale dynamics of the process is numerically studied on examples of simple fiber networks. A discussion of results in light of biological evidence is provided.
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chemotaxis
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cancer invasion model
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multiscale
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numerical simulations
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