\textit{Shigellosis} dynamics: modelling the effects of treatment, sanitation, and education in the presence of carriers (Q2205132)

This paper focus on a Shigellosis model including disease carriers with multiple control strategies is developed. The effective reproductive number \(R_e\) was obtained. Based on this threshold, the dynamics for the model was studied. More specifically, the disease-free equilibrium for the model is locally asymptotically stable if \(R_e < 1\) and unstable if \(R_e > 1\). Further, by using Lyapunov functions, the disease-free equilibrium for the model was shown to be globally asymptotically stable if \(R_e < 1\) and unstable if \(R_e > 1\), while the endemic equilibrium for the model is globally asymptotically stable if \(R_e > 1\). Sensitivity analysis was performed to investigate the parameters that have a high impact on the transmission dynamics of the disease with direct transmission contributing more infections than indirect transmission. Numerical results shown that there is a reduction in the number of infections when at least a single control measure is applied efficiently. Results also shown that carriers play a potential role in the prevalence of Shigellosis and ignoring these individuals could potentially undermine the efforts of containing this epidemic.