Global attractivity, oscillation and Hopf bifurcation for a class of diffusive hematopoiesis models (Q2454692)

It is considered delay differential equation describing diffusive hematopoiesis model \[ \frac{\partial P(t,x)}{\partial t}=\Delta P(t,x)-\gamma P(t,x)+ \frac{\beta P(t-\tau,x)}{1+P^n(t-\tau,x)}\quad\text{in }D=(0,\infty)\times\Omega\tag{1} \] with Neumann boundary condition \(\frac{\partial P(t,x)}{\partial \nu}=0\) on \(\Gamma=(0,\infty)\times\partial\Omega\) and initial condition \(P(\theta,x)=\varphi(\theta,x)\geq 0\) in \(D_\tau=[-\tau,0]\times\overline{\Omega}\), where \(\gamma,\beta\in(0,\infty)\), \(n=0,1\) or \(n>1\), \(\Omega\subset\mathbb R^m\) is a bounded domain with a smooth boundary \(\partial\Omega\), \(\frac{\partial}{\partial\nu}\) denotes the exterior normal derivative on \(\partial\Omega\), and \(\varphi(\theta,x)\) is Hölder continuous in \(D_\tau\) with \(\varphi(0,x)\in C^1(\overline{\Omega})\). At the usage of the method of lower-upper solution pairs for functional partial differential equations, comparison principle and oscillation theory the authors have proved for the equation (1) the theorems on sufficient conditions for global attractivity and oscillation about positive equilibrium. Existence and stability theorems of Hopf bifurcation for (1) are also proved.