The effects of vertical transmission on the spread of HIV/AIDS in the presence of treatment (Q2505117)

The authors formulate and analyze a deterministic HIV model which incorporates treatment of juveniles infected with HIV/AIDS through vertical transmission, and infected adults. They establish the local and global stability of the disease-free equilibrium point. From the stability analysis of this point, they determine the model reproduction number \({\mathfrak A}_0\), which is found to be a decreasing function of the treatment rate \(\sigma\) if \({\mathfrak A}_0>{\mathfrak A}_{0t}\) but an increasing function of \({\mathfrak A}_v\), a parameter which measures the demographic replacement of infectives due to the vertical transmission of HIV/AIDS. Here, \({\mathfrak A}_{0t}= \lim_{\sigma\to\infty}{\mathfrak A}_0\).