A general multipatch cholera model in periodic environments (Q2669211)

This paper studied a general multipatch cholera epidemic model in a periodic environment. The threshold type of result for the model is established based on the basic reproduction number \(\mathcal{R}_0\). Specifically, the disease-free steady state is globally attractive when \(\mathcal{R}_0<1\) if either immigration of hosts is homogeneous or immunity loss of human hosts can be neglected; the disease is uniformly persistent and the system admits at least one positive periodic solution when \(\mathcal{R}_0>1\). Numerical simulations indicates that (a) neglecting asymptotic infections may underestimate the risk of infection; (b) travel can help the disease to become persistent (resp. eradicated) in the network, even though the disease dies out (resp. persists) in each isolated patch.