Mathematical modeling and analysis of the kinetics of thermal inactivation of enzyme (Q275897)

Summary: A theoretical model of [\textit{V. Illeová} et al., ``Experimental modelling of thermal inactivation of urease'', J. Biotechnology 105, No. 3, 235--243 (2003; \url{doi:10.1016/j.jbiotec.2003.07.005})] thermal inactivation of urease is discussed. Analytical expressions pertaining to the molar concentrations of the native and denatured enzyme are obtained in terms of second-order reaction rate constant. Simple and closed form of theoretical expression pertains to the temperature are also derived. In this paper, homotopy analysis method (HAM) is used to obtain approximate solutions for a nonlinear ordinary differential equation. The obtained approximate result in comparison with the numerical ones is found to be in satisfactory agreement.