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    18 September 1994
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    test of trend
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    carcinogenesis
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    ED-01 study
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    dose response
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    long term rodent bioassays
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    tumors
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    multinomial distribution
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    linear logistic
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    Cochran-Armitage type test
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    historical controls
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    Tarone type test
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    conditional Hoel-Yanagawa type test
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    beta priors
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    asymptotic distributions
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    Pitman efficiencies
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    asymptotic equivalence
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