Analysis of similarity/dissimilarity of DNA sequences based on chaos game representation (Q370321)

Summary: The Chaos Game is an algorithm that can allow one to produce pictures of fractal structures. Considering that the four bases A, G, C, and T of DNA sequences can be divided into three classes according to their chemical structure, we propose different kinds of CGR-walk sequences. Based on CGR coordinates of random sequences, we introduce some invariants for the DNA primary sequences. As an application, we can make the examination of similarity/dissimilarity among the first exon of \(\beta \)-globin gene of different species. The results indicate that our method is efficient and can get more biological information.