Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit (Q3748859)
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scientific article; zbMATH DE number 3985015
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| English | Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit |
scientific article; zbMATH DE number 3985015 |
Statements
Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit (English)
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1986
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nonlinear programming method of conjugate-gradient type
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drug kinetics
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pharmacokinetic two-compartment open model
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absorption
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Aspirin
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rabbits
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lysine acetylsalicylate
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sodium salicylate
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transfer
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elimination
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rate constants
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first-order kinetics
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coupled linear differential equations
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numerical tests
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computer simulation study
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finite difference discretization method
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optimal therapeutic treatments
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0.7456619739532471
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0.7210891842842102
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