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The monograph presents constructive numerical-analytic methods of investigating the existence and approximate construction of periodic solutions for autonomous systems and solutions for nonlinear systems of differential equations which satisfy some boundary conditions. The matrix-vector approach is suggested to realize the successive polynomial approximation method when solutions of periodic and two-point boundary value problems are considered. The methods of finding the initial values of solutions of nonlinear periodic and multi-point boundary value problems are substantiated. On the basis of numerical methods the existence conditions of multi-point boundary value problems are determined. The book contains six chapters. In the first chapter the results about existence of periodic solutions for the system \(\dot x=f(x)\), \(x\in E_ n\) are proved. Moreover the estimation of approximative solution and estimation of its period as well as the convergence of successive approximation solutions to precise solution are given. In chapter 2 the nonseparable two-point boundary value problem (1) \(Ax(a)+Bx(b)=d\) for the system (2) \(\dot x=f(t,x)\); \(x,f\in E_ n\), \(t\in[a,b]\) is considered. An algorithm for finding a solution of this problem is constructed. Theorems about existence of a solution are proved. Chapter 3 deals with a method of successive trigonometric approximations for investigation of periodic systems (2). Moreover a method of successive approximations of solutions in the form of algebraic polynomials is considered for (1), (2). Some analogous question are discussed in chapter 4 for systems with retarded argument \(\dot x(t)=f(t,x(t),x(t-\tau))\), \(x\in E_ n\), or for neutral systems \(\dot x(t)=f(t,x(t),x(t-\tau_ 1),\dot x(t),\dot x(t- \tau_ 2))\) and for periodic problems, (3) \(x(0)=x(T)\), or for multipoint boundary value problems, (4) \(\sum_{j=0}^ s B_ j x(t_ j)=d\). In chapter 5 the problems (3), (4) for the system (5) \(\dot x=A(t)x+f(t)\) are investigated. Some approximative equations for finding initial values for the problems (3), (5) and (4), (5) are given. Chapter 6 is devoted to the problems (2), (3); (2), (1); (2), (4) and (2), (6) where (6) \(L(x(t_ 0),x(t_ 1),\dots,x(t_ n))=0\) are nonlinear conditions. Approximative equations giving initial values of these problems are constructed. Moreover, in this book many theoretical results about the considered problems are proved. The constructed algorithms are suitable for numerical computations. Interesting illustrative numerical examples from electrical engineering are computed.