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scientific article; zbMATH DE number 1984917
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scientific article; zbMATH DE number 1984917 |
Statements
23 September 2003
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0.9374583
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0.9297644
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0.91904503
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0.90668094
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0.88419944
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This book provides excellent survey articles on most commonly used biostatistical tools for clinical research. The articles cover the whole range of clinical research, starting from Phase I and II trials for drug development, Phase III randomized clinical trials and more complex issues such as compliance in treatment evaluation. The major emphasis is on Phase III trials (7 out of 12 articles). Important problems such as equivalence trials, adaptive designs, multiple endpoints and subgroup analyses are addressed. One important problem missing are the group sequential methods. The book is recommended for biostatistics graduate students and practitioners. I support this recommendation.
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