Statistical methods in human genetics (Q4938838)

Statistics and human genetics are twin subjects, having grown with the century together, and there are many connections between the two. Some fundamental ideas in statistics, in particular the concept of the Analysis of Variance, first arose in human genetics, while statistical and probabilistic methods are now central to many aspects of the analysis of questions in the human genetics. The aim of this paper is to describe three particular applications of statistical methods in human genetics. The first two of these relate to the Human Genome Project, while the third concerns linkage analysis, especially linkage analysis as used for finding disease genes. Many other areas could be discussed, and the three described below were chosen to give an indication of the variety of probabilistic and statistical methods used in human genetics, as well as reflecting the interests of the author. For the entire collection see [Zbl 0932.00050].