Testing for one-sided group effects in repeated measures study (Q5941552)

In repeated measures experiments, one-sided tests for group effects are developed using the likelihood ratio principle. The constrained maximum likelihood estimators under hypotheses of one-sided group effects are approximated by projecting unconstrained maximum likelihood estimators onto the first quadrant. From these constrained maximum likelihood estimators, likelihood ratio tests are constructed. The limiting null distributions of the proposed test statistics are shown to be chi-bar square distributions. A simulation study shows that the proposed tests have improved power over the usual chi-square statistics for testing group effects. Two real data sets are analyzed to illustrate the proposed statistics.