upndown (Q5984503)

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Utilities and Design Aids for Up-and-Down Dose-Finding Studies
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    upndown
    Utilities and Design Aids for Up-and-Down Dose-Finding Studies

      Statements

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      0.1.0
      7 June 2023
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      PACKAGES.rds
      9 July 2026
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      0.2.0
      10 December 2024
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      0.3.0
      16 June 2025
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      Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2024 <doi:10.51387/24-NEJSDS74>.
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      16 June 2025
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