upndown

MaRDI QIDQ5984503CRANFDO

Authors Assaf P. Oron

Last update 16 June 2025

Copyright license GNU General Public License, version 2.0

Software version identifier 0.1.0, PACKAGES.rds, 0.2.0, 0.3.0

Description

Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2024 <doi:10.51387/24-NEJSDS74>.

Cites work

• Understanding Research Methods: Up-and-down Designs for Dose-finding
• Up-and-Down: The Most Popular, Most Reliable, and Most Overlooked Dose-Finding Design

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