Classifying the post-duplication fate of paralogous genes (Q6086491)
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scientific article; zbMATH DE number 7777111
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| English | Classifying the post-duplication fate of paralogous genes |
scientific article; zbMATH DE number 7777111 |
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Classifying the post-duplication fate of paralogous genes (English)
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12 December 2023
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The paper describes a computational framework for the characterisation of duplicated genes and a formal feature-based differentiation of fates which allows the identification of novel patterns. To illustrate the steps, the authors simulate the evaluation of populations using aevol. The post-duplications fates described in detail include pseudogenization, double-neofunctionalisation, conservation, subfunctionalisation and specialisation. All mathematical and computational aspects of the study are described in detail. For the entire collection see [Zbl 1525.92003].
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gene duplication
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duplication fates
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classification
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paralogy
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simulation
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0.7021917104721069
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0.668489396572113
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0.6578866839408875
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0.6524145007133484
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0.6460286974906921
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