gsDesign2 (Q64032)
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Group Sequential Design with Non-Constant Effect
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | gsDesign2 |
Group Sequential Design with Non-Constant Effect |
Statements
9 February 2024
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The goal of 'gsDesign2' is to enable fixed or group sequential design under non-proportional hazards. To enable highly flexible enrollment, time-to-event and time-to-dropout assumptions, 'gsDesign2' offers piecewise constant enrollment, failure rates, and dropout rates for a stratified population. This package includes three methods for designs: average hazard ratio, weighted logrank tests in Yung and Liu (2019) <doi:10.1111/biom.13196>, and MaxCombo tests. Substantial flexibility on top of what is in the 'gsDesign' package is intended for selecting boundaries.
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