Quantitative Multi-Modal Optical Coherence Photoacoustic Elastography (Q7266572)

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    Quantitative Multi-Modal Optical Coherence Photoacoustic Elastography
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      Quantitative Multi-Modal Optical Coherence Photoacoustic Elastography (English)
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      17 June 2026
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      physics.med-ph
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      math.NA
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      Ekaterina Sherina
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      Lisa Krainz
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      Wolfgang Drexler
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      Otmar Scherzer
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      This study introduces a novel multi-modal framework combining optical coherence tomography and photoacoustic tomography to enable quantitative tissue feature extraction via quasi-static elastography. Systematic evaluations demonstrate that their hybrid inversion algorithm yields superior strain signal-to-noise ratios and improved stiffness estimates compared to single-modality methods in both absorbing and scattering materials.
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      Multimodal Imaging
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      Photoacoustic Tomography
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      Optical Elastography
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      Hybrid Inversion
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      Quantitative Mapping
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