rxode2lincmt (Q7369925)
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Linear Compartment Model Solutions and Gradients for 'rxode2'
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | No label defined |
||
| English | rxode2lincmt |
Linear Compartment Model Solutions and Gradients for 'rxode2' |
Statements
Analytic one, two and three compartment linear pharmacokinetic solutions with their parameter gradients from 'stan' automatic differentiation (Carpenter et al (2015) <doi:10.48550/arXiv.1509.07164>), eigen decompositions and derived-parameter conversions used by 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>). Split out of 'rxode2' so its installation does not compile 'stan' AD items which made it take too long to compile by itself. The closed-form solutions follow the idea of the 'wnl' package (Bae, <https://CRAN.R-project.org/package=wnl>), though the implementation here is different.
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24 September 2026
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