rxode2lincmt

MaRDI QIDQ7369925CRANFDO

Authors Matthew L. Fidler

Last update 24 September 2026

Copyright license GNU General Public License

Software version identifier 0.1.0

Description

Analytic one, two and three compartment linear pharmacokinetic solutions with their parameter gradients from 'stan' automatic differentiation (Carpenter et al (2015) <doi:10.48550/arXiv.1509.07164>), eigen decompositions and derived-parameter conversions used by 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>). Split out of 'rxode2' so its installation does not compile 'stan' AD items which made it take too long to compile by itself. The closed-form solutions follow the idea of the 'wnl' package (Bae, <https://CRAN.R-project.org/package=wnl>), though the implementation here is different.

Cites work

• A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R

Cited in

(1)

• rxode2

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