InfluenceBorrowing (Q7378588)
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Adaptive Influence-Based Borrowing for Hybrid Control Trials
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| default for all languages | No label defined |
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| English | InfluenceBorrowing |
Adaptive Influence-Based Borrowing for Hybrid Control Trials |
Statements
Implements the adaptive influence-based borrowing framework proposed by Qinwei Yang, Jingyi Li, Peng Wu, and Shu Yang (2026+) in the paper “Improving Treatment Effect Estimation in Trials through Adaptive Borrowing of External Controls" <doi:10.48550/arXiv.2604.13973> for augmenting Randomized Controlled Trials (RCTs) with External Control (EC) data. This package provides a comprehensive workflow to: (1) quantify the comparability of external control samples using influence scores approximated via the influence function of the M-estimator; (2) construct candidate borrowing subsets and select the optimal subset that minimizes the Mean Squared Error (MSE); and (3) calibrate systematic differences in external outcomes using R-learner methods implemented via Ordinary Least Squares or Kernel Ridge Regression.
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23 April 2026
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Peng Wu
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Shu Yang
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