Local alignment of Markov chains (Q862205)

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scientific article; zbMATH DE number 5121982
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    Local alignment of Markov chains
    scientific article; zbMATH DE number 5121982

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      Local alignment of Markov chains (English)
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      5 February 2007
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      This paper investigates local alignments without gaps of two independent Markov chains from a finite alphabet. Sufficient conditions are established for the number of essentially different local alignments with a score exceeding a high threshold to be asymptotically Poisson distributed. From the Poisson approximation a Gumbel approximation of the maximal local alignment score is obtained. The results extend known results for independent sequences of i.i.d random variables.
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      Chen-Stein method
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      extreme value theory
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      large deviations
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      local alignment
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      Markov additive processes
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      Poisson approximation
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