Allele frequencies in multigene families. I: Diffusion equation approach (Q909596)
From MaRDI portal
scientific article
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Allele frequencies in multigene families. I: Diffusion equation approach |
scientific article |
Statements
Allele frequencies in multigene families. I: Diffusion equation approach (English)
0 references
1989
0 references
This paper explores several properties of a model of \textit{A. Shimizu} [see Stochastic methods in biology, Proc. Workshop, Nagoya/Jap. 1985, Lect. Notes Biomath. 70, 100-114 (1987; Zbl 0644.92010)] for the evolution of a population of chromosomes using a diffusion approach. The model includes mutation and gene conversion within a multigene family on the chromosomes. In particular, the author shows why Ewens sampling formula emerges in this context. The theory is also extended to obtain transient and stationary results for the sampling distribution. Expectations, variances and covariances for the numbers of alleles across the chromosomes are calculated. Some numerical examples are included.
0 references
diffusion equation approach
0 references
mutation
0 references
gene conversion
0 references
multigene family
0 references
Ewens sampling formula
0 references
transient and stationary results
0 references
sampling distribution
0 references
Expectations
0 references
variances
0 references
covariances
0 references
numbers of alleles
0 references
numerical examples
0 references
0 references
0 references
0 references
