Loss-Function Learning for Digital Tissue Deconvolution

DOI10.1007/978-3-319-89929-9_5MaRDI QIDQ5881342zbMATH OpenOpenAlexFDO

Authors Stefan Solbrig, Rainer Spang, T. Wettig

Publication date 9 March 2023

Published in Lecture Notes in Computer Science (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1801.08447

zbMATH Keywords

bulk profilecancer-associated fibroblasts (CAFs)reference profilesimilar cell typessmall cell population

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Cell biology (92C37) Biochemistry, molecular biology (92C40)

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(5)

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• BayICE: a Bayesian hierarchical model for semireference-based deconvolution of bulk transcriptomic data
• Disentangled representations of cellular identity
• ICeD-t provides accurate estimates of immune cell abundance in tumor samples by allowing for aberrant gene expression patterns
• Estimating Cell Type Composition Using Isoform Expression One Gene at a Time

Describes a project that uses

Uses Software

• pbdR
• pbdMPI

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