Mathematical modeling in full-field optical coherence elastography
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biological tissueselastographyfull-field optical coherence tomographyhigh-resolution shear modulus imaginghybrid imagingoptimal control
Dependence of solutions to PDEs on initial and/or boundary data and/or on parameters of PDEs (35B30) PDEs in connection with fluid mechanics (35Q35) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Inverse problems for PDEs (35R30) Biomedical imaging and signal processing (92C55)
Abstract: We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, real-time processing, and non-invasive imaging. We develop a novel algorithm for transforming volumetric optical images before and after the mechanical solicitation of a sample with sub-cellular resolution into quantitative shear modulus distributions. This has the potential to improve sensitivities and specificities in the biological and clinical applications of optical coherence tomography.
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Cites work
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Cited in
(6)- A direct linear inversion for discontinuous elastic parameters recovery from internal displacement information only
- Reconstructing the Optical Parameters of a Layered Medium with Optical Coherence Elastography
- Displacement field estimation from OCT images utilizing speckle information with applications in quantitative elastography
- Subaperture-Based Digital Aberration Correction for Optical Coherence Tomography: A Novel Mathematical Approach
- Time-harmonic optical flow with applications in elastography
- On the intensity-based inversion method for quantitative quasi-static elastography
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